@article{Srivastava2022a, author = "H. Srivastava and R. Canfield and M. P. Lam and E. Lau", title = "Post-transcriptional regulation of protein abundance by protein interaction partners", year = 2022, journal = "bioRxiv", url = "https://www.biorxiv.org/content/10.1101/2022.03.14.484316v2" } @article{Han2022b, author = "Y. Han and S. A. Wennersten and J. M. Wright and R. W. Ludwig and E. Lau and M. P. Y. Lam", title = "Proteogenomics Reveals Sex-biased Aging Genes and Coordinated Splicing in Cardiac Aging", year = 2022, journal = "Am J Physiol Heart Circ Physiol", volume = 1, number = 3233, pages = "H538-H558", month = "Sep", doi = "10.1152/ajpheart.00244.2022.", url = "https://journals.physiology.org/doi/abs/10.1152/ajpheart.00244.2022?rfr_dat=cr_pub++0pubmed&url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org" } @article{Han2022a, author = "Y. Han and S. A. Wennersten and J. Wright and R. W. Ludwig and E. Lau and M. P. Lam", title = "Proteogenomic characterization of age and sex interactions in cardiac gene expression", year = 2022, journal = "bioRxiv", month = "May", url = "https://www.biorxiv.org/content/10.1101/2022.05.11.491401v1" } @article{Lin2022a, author = "Y. H. Lin and J. L. Major and T. Liebner and Z. Hourani and J. G. Travers and S. A. Wennersten and K. R. Haefner and M. A. Cavasin and C. E. Wilson and M. Y. Jeong and Y. Han and M. Gotthardt and S. K. Ferguson and A. V. Ambardekar and M. P. Lam and C. Choudhary and H. L. Granzier and K. C. Woulfe and M. TA.", title = "HDAC6 modulates myofibril stiffness and diastolic function of the heart.", year = 2022, journal = "J Clin Invest.", month = "May", url = "https://pubmed.ncbi.nlm.nih.gov/35575093/" } @article{Han2021c, author = "Y. Han and L. Z. Li and N. L. Kastury and C. T. Thomas and M. P. Y. Lam and E. Lau", title = "Transcriptome features of striated muscle aging and predictability of protein level changes", year = 2021, journal = "Mol Omics", month = "Oct", url = "https://pubmed.ncbi.nlm.nih.gov/34328155/" } @article{Han2021b, author = "Y. Han and C. T. Thomas and S. A. Wennersten and E. Lau and M. P. Y. Lam", title = "Shotgun Proteomics Sample Processing Automated by an Open-Source Lab Robot", year = 2021, journal = "J Vis Exp", month = "Oct", url = "https://pubmed.ncbi.nlm.nih.gov/34779440/" } @article{Travers2021a, author = "J. G. Travers and S. A. Wennersten and B. Peña and R. A. Bagchi and H. E. Smith and R. A. Hirsch and L. A. Vanderlinden and Y. H. Lin and E. Dobrinskikh and K. M. Demos-Davies and M. A. Cavasin and L. Mestroni and C. Steinkühler and C. Y. Lin and S. R. Houser and K. C. Woulfe and M. P. Y. Lam and T. A. McKinsey", title = "HDAC Inhibition Reverses Preexisting Diastolic Dysfunction and Blocks Covert Extracellular Matrix Remodeling", year = 2021, journal = "Circulation", month = "May", url = "https://pubmed.ncbi.nlm.nih.gov/33682427/" } @article{Chour2021a, author = "T. Chour and L. Tian and E. Lau and D. Thomas and Itzhaki I and O. Malak and J. Z. Zhang and X. Qin and M. Wardak and Y. Liu and M. Chandy and K. E. Black and M. P. Lam and E. Neofytou and J. C. Wu", title = "Method for selective ablation of undifferentiated human pluripotent stem cell populations for cell-based therapies", year = 2021, journal = "JCI Insight", month = "Apr", url = "https://pubmed.ncbi.nlm.nih.gov/33830086/" } @article{Han2021a, author = "Y. Han and S. D. Wood and J. M. Wright and V. Dostal and E. Lau and M. P. Y. Lam", title = "Computation-assisted targeted proteomics of alternative splicing protein isoforms in the human heart", year = 2021, journal = "J Mol Cell Cardiol", volume = 154, pages = "92-96", month = "Feb", keywords = "isoforms, proteomics", url = "https://pubmed.ncbi.nlm.nih.gov/33549679/" } @article{Han2020a, author = "Y. Han and J. M. Wright and E. Lau and M. P. Y. Lam", title = "Determining Alternative Protein Isoform Expression Using RNA Sequencing and Mass Spectrometry", year = 2020, journal = "STAR Protocols", volume = 1, number = 3, pages = "100138", month = "Oct", keywords = "proteoforms", doi = "10.1016/j.xpro.2020.100138", url = "https://www.sciencedirect.com/science/article/pii/S2666166720301258" } @article{Adhikari2020a, author = "S. Adhikari and E. C. Nice and E. W. Deutsch and L. Lane and G. S. Omenn and S. R. Pennington and Y. K. Paik and C. M. Overall and F. J. Corrales and I. M. Cristea and J. E. V. Eyk and M. Uhlén and C. Lindskog and D. W. Chan and A. Bairoch and J. C. Waddington and J. L. Justice and J. LaBaer and H. Rodriguez and F. He and M. Kostrzewa and P. Ping and R. L. Gundry and P. Stewart and S. Srivastava and S. Srivastava and F. C. S. Nogueira and G. B. Domont and Y. Vandenbrouck and M. P. Y. Lam and S. Wennersten and J. A. Vizcaino and M. Wilkins and J. M. Schwenk and E. Lundberg and N. Bandeira and G. Marko-Varga and S. T. Weintraub and C. Pineau and U. Kusebauch and R. L. Moritz and S. B. Ahn and M. Palmblad and M. P. Snyder and R. Aebersold and B. MS.", title = "A high-stringency blueprint of the human proteome", year = 2020, journal = "Nature Communications", volume = 11, number = 1, pages = "5301", month = "Oct", keywords = "hupo", url = "https://pubmed.ncbi.nlm.nih.gov/33067450/" } @article{Dostal2020a, author = "V. Dostal and S. D. Wood and C. T. Thomas and E. Y. Han and E. Lau and M. P. Y. Lam", title = "Proteomic signatures of acute oxidative stress response to paraquat in the mouse heart", year = 2020, journal = "bioRxiv", month = "May", keywords = "heart, proteomics, oxidative stress, proteostasis", doi = "https://doi.org/10.1101/2020.05.29.124487", url = "https://www.biorxiv.org/content/10.1101/2020.05.29.124487v1" } @article{pmid31822126, author = "Y. Han and S. A. Wennersten and M. P. Y. Lam", title = "{W}orking the literature harder: what can text mining and bibliometric analysis reveal?", year = 2019, journal = "Expert Rev Proteomics", volume = 16, number = 1112, keywords = "bioinformatics, bibliometrics, popular proteins, hupo", url = "https://pubmed.ncbi.nlm.nih.gov/31822126/" } @article{Lau2019a, author = "E. Lau and Y. Han and D. R. Williams and C. T. Thomas and R. Shrestha and J. C. Wu and M. P. Lam", title = "Splice-Junction-Based Mapping of Alternative Isoforms in the Human Proteome.", year = 2019, journal = "Cell Reports", volume = 29, number = 11, pages = "3751-3765", month = "Dec", keywords = "alternative splicing, mass spectrometry, bioinformatics, proteoforms", doi = "10.1016/j.celrep.2019.11.026" } @article{Ruiz-Romero2019a, author = "C. Ruiz-Romero and M. P. Y. Lam and P. Nilsson and P. Önnerfjord and P. J. Utz and J. E. V. Eyk and Venkatraman V and J. Fert-Bober and F. E. Watt and F. J. Blanco", title = "Mining the Proteome Associated with Rheumatic and Autoimmune Diseases.", year = 2019, journal = "Journal of Proteome Research", volume = 18, number = 12, pages = "4231-4239", month = "Oct", keywords = "bioinformatics, bibliometrics, popular proteins, hupo", doi = "10.1021/acs.jproteome.9b0036", url = "https://www.ncbi.nlm.nih.gov/pubmed/31599600" } @article{pmid31409188, author = "M. S. Stratton and R. A. Bagchi and M. B. Felisbino and R. A. Hirsch and H. E. Smith and A. S. Riching and B. Y. Enyart and K. A. Koch and M. A. Cavasin and M. Alexanian and K. Song and J. Qi and M. E. Lemieux and D. Srivastava and M. P. Y. Lam and S. M. Haldar and C. Y. Lin and T. A. McKinsey", title = "{D}ynamic {C}hromatin {T}argeting of {B}{R}{D}4 {S}timulates {C}ardiac {F}ibroblast {A}ctivation", year = 2019, journal = "Circ. Res.", volume = 125, number = 7, month = "Sep", keywords = "mass spectrometry, fibrosis", doi = "https://dx.doi.org/10.1161/CIRCRESAHA.119.31512510.1161/CIRCRESAHA.119.315125" } @article{doi:10.1021/acs.jproteome.8b00393, author = "E. Lau and V. Venkatraman and C. T. Thomas and J. C. Wu and J. E. V. Eyk and M. Lam", title = "Identifying high-priority proteins across the human diseasome using semantic similarity", year = 2018, journal = "Journal of Proteome Research", month = "Sep", keywords = "bioinformatics, bibliometrics, popular proteins, hupo", doi = "10.1021/acs.jproteome.8b00393", url = "https://doi.org/10.1021/acs.jproteome.8b00393" } @inbook{Lau2018e, author = "E. Lau and M. P. Y. Lam", title = "Research trends and focuses in the ubiquitin-proteasome system: a bibliometric analysis", year = 2018, booktitle = "Ubiquitin Proteasome System: A Review and Directions for Research.", publisher = "Nova Publishers", month = "Jul", keywords = "book chapter, protein turnover", url = "https://novapublishers.com/shop/ubiquitin-proteasome-system-a-review-and-directions-for-research/", note = "Series: Cell Biology Research Progress", isbn = "978-1-53613-518-3" } @article{Lau372995, author = "E. Lau and M. P. Y. Lam", title = "Identifying alternative splicing isoforms in the human proteome with small proteotranscriptomic databases", year = 2018, journal = "bioRxiv", publisher = "Cold Spring Harbor Laboratory", month = "Jul", keywords = "preprint, alternative splicing, mass spectrometry, bioinformatics, proteoforms", doi = "10.1101/372995", url = "https://www.biorxiv.org/content/early/2018/07/27/372995" } @article{Lau309203, author = "E. Lau and V. Venkatraman and C. T. Thomas and J. E. V. Eyk and M. P. Y. Lam", title = "Identifying high-priority proteins across the human diseasome using semantic similarity", year = 2018, journal = "bioRxiv", publisher = "Cold Spring Harbor Laboratory", month = "Jun", keywords = "preprint, popular proteins, bibliometrics", doi = "10.1101/309203", url = "https://www.biorxiv.org/content/early/2018/04/29/309203" } @article{pmid29506994, author = "M. P. Y. Lam and Y. Ge", title = "{H}arnessing the {P}ower of {P}roteomics to {A}ssess {D}rug {S}afety and {G}uide {C}linical {T}rials", year = 2018, journal = "Circulation", volume = 137, number = 10, month = "Mar" } @article{pmid29317621, author = "E. Lau and Q. Cao and M. P. Y. Lam and J. Wang and D. C. M. Ng and B. J. Bleakley and J. M. Lee and D. A. Liem and D. Wang and H. Hermjakob and P. Ping", title = "{I}ntegrated omics dissection of proteome dynamics during cardiac remodeling", year = 2018, journal = "Nat Commun", volume = 9, number = 1, month = "Jan", keywords = "mass spectrometry, bioinformatics, protein turnover, proteostasis" } @inproceedings{Lam2017a, author = "M. P. Lam and P. Ping and Y. Xing", title = "Integrated omics analysis of isoform switching under cardiac hypertrophy", year = 2017, journal = "Journal of Molecular and Cellular Cardiology", volume = 112, pages = "164-165", keywords = "alternative splicing, proteoforms", doi = "https://doi.org/10.1016/j.yjmcc.2017.07.101" } @inproceedings{Lau2017a, author = "E. Lau and M. P. Lam and P. Ping", title = "Multi-omics approach to identify disease signatures in cardiac remodeling", year = 2017, journal = "Journal of Molecular and Cellular Cardiology", volume = 112, pages = "154-155", month = "Nov" } @article{pmid28007144, author = "M. P. Lam and P. Ping and E. Murphy", title = "{P}roteomics research in cardiovascular medicine and biomarker discovery", year = 2016, journal = "J. Am. Coll. Cardiol.", volume = 68, number = 25, month = "Dec", keywords = "proteomics, cardiovascular" } @article{pmid27356587, author = "M. P. Lam and V. Venkatraman and Y. Xing and E. Lau and Q. Cao and D. C. Ng and A. I. Su and J. Ge and J. E. V. Eyk and P. Ping", title = "{D}ata-driven approach to determine popular proteins for targeted proteomics translation of six organ systems", year = 2016, journal = "J. Proteome Res.", volume = 15, number = 11, month = "Nov", keywords = "bibliometrics, hupo" } @article{pmid26463451, author = "A. Yee and M. P. Lam and V. Tam and W. C. Chan and I. K. Chu and K. S. Cheah and K. M. Cheung and D. Chan", title = "{F}ibrotic-like changes in degenerate human intervertebral discs revealed by quantitative proteomic analysis", year = 2016, journal = "Osteoarthr. Cartil.", volume = 24, number = 3, month = "Mar", keywords = "proteomics, fibrosis" } @article{pmid26977904, author = "E. Lau and Q. Cao and D. C. Ng and B. J. Bleakley and T. U. Dincer and B. M. Bot and D. Wang and D. A. Liem and M. P. Lam and J. Ge and P. Ping", title = "{A} large dataset of protein dynamics in the mammalian heart proteome", year = 2016, journal = "Sci Data", volume = 3, month = "Mar", keywords = "protein turnover, heavy water, mass spectrometry" } @article{pmid26821878, author = "L. Lin and P. Jiang and J. W. Park and J. Wang and Z. X. Lu and M. P. Lam and P. Ping and Y. Xing", title = "{T}he contribution of {A}lu exons to the human proteome", year = 2016, journal = "Genome Biol.", volume = 17, month = "Jan" } @article{pmid27980500, author = "M. P. Lam and E. Lau and D. C. Ng and D. Wang and P. Ping", title = "{C}ardiovascular proteomics in the era of big data: experimental and computational advances", year = 2016, journal = "Clin Proteomics", volume = 13 } @article{pmid26160638, author = "M. P. Lam and V. Venkatraman and Q. Cao and D. Wang and T. U. Dincer and E. Lau and A. I. Su and Y. Xing and J. Ge and P. Ping and J. E. V. Eyk", title = "{P}rioritizing proteomics assay development for clinical translation", year = 2015, journal = "J. Am. Coll. Cardiol.", volume = 66, number = 2, month = "Jul" } @article{pmid25752359, author = "E. Lau and D. Huang and Q. Cao and T. U. Dincer and C. M. Black and A. J. Lin and J. M. Lee and D. Wang and D. A. Liem and M. P. Lam and P. Ping", title = "{S}patial and temporal dynamics of the cardiac mitochondrial proteome", year = 2015, journal = "Expert Rev Proteomics", volume = 12, number = 2, month = "Apr", keywords = "protein turnover, cardiovascular, mitochondria" } @article{pmid24946186, author = "D. Wang and D. A. Liem and E. Lau and D. C. Ng and B. J. Bleakley and M. Cadeiras and M. C. Deng and M. P. Lam and P. Ping", title = "{C}haracterization of human plasma proteome dynamics using deuterium oxide", year = 2014, journal = "Proteomics Clin Appl", volume = 8, number = 78, month = "Aug", keywords = "protein turnover, human plasma, heavy water" } @article{pmid24957502, author = "N. Zong and P. Ping and E. Lau and H. J. Choi and D. C. Ng and D. Meyer and C. Fang and H. Li and D. Wang and I. M. Zelaya and J. R. Yates and M. P. Lam", title = "{L}ysine ubiquitination and acetylation of human cardiac 20{S} proteasomes", year = 2014, journal = "Proteomics Clin Appl", volume = 8, number = 78, month = "Aug", keywords = "protein turnover, cardiovascular" } @article{pmid24614109, author = "M. P. Lam and D. Wang and E. Lau and D. A. Liem and A. K. Kim and D. C. Ng and X. Liang and B. J. Bleakley and C. Liu and J. D. Tabaraki and M. Cadeiras and Y. Wang and M. C. Deng and P. Ping", title = "{P}rotein kinetic signatures of the remodeling heart following isoproterenol stimulation", year = 2014, journal = "J. Clin. Invest.", volume = 124, number = 4, month = "Apr", keywords = "protein turnover, cardiovascular, human plasma, heavy water, mass spectrometry" } @article{pmid24791980, author = "M. P. Lam and C. H. Law and Q. Quan and Y. Zhao and I. K. Chu", title = "{F}ully automatable multidimensional reversed-phase liquid chromatography with online tandem mass spectrometry", year = 2014, journal = "Methods Mol. Biol.", volume = 1156 } @article{pmid24311610, author = "M. P. Lam and E. Lau and D. A. Liem and P. Ping", title = "{C}yclophilin {D} and acetylation: a new link in cardiac signaling", year = 2013, journal = "Circ. Res.", volume = 113, number = 12, month = "Dec", keywords = "cardiovascular" } @article{pmid24014600, author = "C. L. Lee and M. P. Lam and K. K. Lam and C. O. Leung and R. T. Pang and I. K. Chu and T. H. Wan and J. Chai and W. S. Yeung and P. C. Chiu", title = "{I}dentification of {C}{D}147 (basigin) as a mediator of trophoblast functions", year = 2013, journal = "Hum. Reprod.", volume = 28, number = 11, month = "Nov" } @article{pmid23965338, author = "N. C. Zong and H. Li and H. Li and M. P. Lam and R. C. Jimenez and C. S. Kim and N. Deng and A. K. Kim and J. H. Choi and I. Zelaya and D. Liem and D. Meyer and J. Odeberg and C. Fang and H. J. Lu and T. Xu and J. Weiss and H. Duan and M. Uhlen and J. R. Yates and R. Apweiler and J. Ge and H. Hermjakob and P. Ping", title = "{I}ntegration of cardiac proteome biology and medicine by a specialized knowledgebase", year = 2013, journal = "Circ. Res.", volume = 113, number = 9, month = "Oct" } @article{pmid23022582, author = "M. P. Lam and E. Lau and S. B. Scruggs and D. Wang and T. Y. Kim and D. A. Liem and J. Zhang and C. M. Ryan and K. F. Faull and P. Ping", title = "{S}ite-specific quantitative analysis of cardiac mitochondrial protein phosphorylation", year = 2013, journal = "J Proteomics", volume = 81, month = "Apr" } @article{pmid23242529, author = "B. S. Wong and K. K. Lam and C. L. Lee and V. H. Wong and M. P. Lam and I. K. Chu and W. S. Yeung and P. C. Chiu", title = "{A}drenomedullin enhances invasion of human extravillous cytotrophoblast-derived cell lines by regulation of urokinase plasminogen activator expression and s-nitrosylation", year = 2013, journal = "Biol. Reprod.", volume = 88, number = 2, month = "Feb" } @article{pmid22915825, author = "T. Y. Kim and D. Wang and A. K. Kim and E. Lau and A. J. Lin and D. A. Liem and J. Zhang and N. C. Zong and M. P. Lam and P. Ping", title = "{M}etabolic labeling reveals proteome dynamics of mouse mitochondria", year = 2012, journal = "Mol. Cell Proteomics", volume = 11, number = 12, month = "Dec", keywords = "protein turnover, heavy water, mitochondria, mass spectrometry" } @article{pmid22387130, author = "M. P. Lam and S. B. Scruggs and T. Y. Kim and C. Zong and E. Lau and D. Wang and C. M. Ryan and K. F. Faull and P. Ping", title = "{A}n {M}{R}{M}-based workflow for quantifying cardiac mitochondrial protein phosphorylation in murine and human tissue", year = 2012, journal = "J Proteomics", volume = 75, number = 15, month = "Aug" } @article{pmid22807358, author = "Y. Zhao and R. P. Kong and G. Li and M. P. Lam and C. H. Law and S. M. Lee and H. C. Lam and I. K. Chu", title = "{F}ully automatable two-dimensional hydrophilic interaction liquid chromatography-reversed phase liquid chromatography with online tandem mass spectrometry for shotgun proteomics", year = 2012, journal = "J Sep Sci", volume = 35, number = 14, month = "Jul" } @article{pmid22641634, author = "J. Zhang and A. Lin and J. Powers and M. P. Lam and C. Lotz and D. Liem and E. Lau and D. Wang and N. Deng and P. Korge and N. C. Zong and H. Cai and J. Weiss and P. Ping", title = "{P}erspectives on: {S}{G}{P} symposium on mitochondrial physiology and medicine: mitochondrial proteome design: from molecular identity to pathophysiological regulation", year = 2012, journal = "J. Gen. Physiol.", volume = 139, number = 6, month = "Jun" } @article{pmid22456183, author = "E. Lau and D. Wang and J. Zhang and H. Yu and M. P. Lam and X. Liang and N. Zong and T. Y. Kim and P. Ping", title = "{S}ubstrate- and isoform-specific proteome stability in normal and stressed cardiac mitochondria", year = 2012, journal = "Circ. Res.", volume = 110, number = 9, month = "Apr", keywords = "protein turnover, cardiovascular, mitochondria" } @article{pmid22539426, author = "M. P. Lam and F. Vivanco and A. Scholten and H. Hermjakob and J. V. Eyk and P. Ping", title = "{H}{U}{P}{O} 2011: {T}he new {C}ardiovascular {I}nitiative - integrating proteomics and cardiovascular biology in health and disease", year = 2012, journal = "Proteomics", volume = 12, number = 6, month = "Mar" } @article{pmid22009802, author = "M. P. Lam and E. Lau and S. O. Siu and D. C. Ng and R. P. Kong and P. C. Chiu and W. S. Yeung and C. Lo and I. K. Chu", title = "{O}nline combination of reversed-phase/reversed-phase and porous graphitic carbon liquid chromatography for multicomponent separation of proteomics and glycoproteomics samples", year = 2011, journal = "Electrophoresis", volume = 32, number = 21, month = "Nov" } @article{pmid21548098, author = "S. O. Siu and M. P. Lam and E. Lau and R. P. Kong and S. M. Lee and I. K. Chu", title = "{F}ully automatable two-dimensional reversed-phase capillary liquid chromatography with online tandem mass spectrometry for shotgun proteomics", year = 2011, journal = "Proteomics", volume = 11, number = 11, month = "Jun" } @article{pmid21350782, author = "E. Lau and M. P. Lam and S. O. Siu and R. P. Kong and W. L. Chan and Z. Zhou and J. Huang and C. Lo and I. K. Chu", title = "{C}ombinatorial use of offline {S}{C}{X} and online {R}{P}-{R}{P} liquid chromatography for i{T}{R}{A}{Q}-based quantitative proteomics applications", year = 2011, journal = "Mol Biosyst", volume = 7, number = 5, month = "May" } @article{pmid20632160, author = "M. P. Lam and S. O. Siu and E. Lau and X. Mao and H. Z. Sun and P. C. Chiu and W. S. Yeung and D. M. Cox and I. K. Chu", title = "{O}nline coupling of reverse-phase and hydrophilic interaction liquid chromatography for protein and glycoprotein characterization", year = 2010, journal = "Anal Bioanal Chem", volume = 398, number = 2, month = "Sep" } @article{pmid20456051, author = "H. Liu and E. Lau and M. P. Lam and H. Chu and S. Li and G. Huang and P. Guo and J. Wang and L. Jiang and I. K. Chu and C. Lo and Y. Tao", title = "{O}s{N}{O}{A}1/{R}{I}{F}1 is a functional homolog of {A}t{N}{O}{A}1/{R}{I}{F}1: implication for a highly conserved plant c{G}{T}{P}ase essential for chloroplast function", year = 2010, journal = "New Phytol.", volume = 187, number = 1, month = "Jul" } @article{pmid19882125, author = "S. O. Siu and M. P. Lam and E. Lau and W. S. Yeung and D. M. Cox and I. K. Chu", title = "{N}-linked glycoprotein analysis using dual-extraction ultrahigh-performance liquid chromatography and electrospray tandem mass spectrometry", year = 2010, journal = "Methods Mol. Biol.", volume = 600 }